Alterity Therapeutics Limited focuses on developing therapies to treat neurodegenerative diseases associated with aging, like Alzheimer's and Parkinson's disease. The company leverages a novel drug development platform aimed at targeting misfolded proteins. Positioned as a pioneer in this field, Alterity aims to address significant unmet needs in the neurosciences market.
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Industry & Focus
biotechnology
neurodegenerative diseases
therapeutic development
pharmaceuticals
aged care
Company Overview
AI-generated company summary
Alterity Therapeutics Limited focuses on developing therapies to treat neurodegenerative diseases associated with aging, like Alzheimer's and Parkinson's disease. The company leverages a novel drug development platform aimed at targeting misfolded proteins. Positioned as a pioneer in this field, Alterity aims to address significant unmet needs in the neurosciences market.
Company History
Alterity Therapeutics Limited, originally known as Prana Biotechnology, was founded in 1997 in Melbourne, Australia. It initially went public on the ASX in 2000, focusing on therapeutic solutions for neurodegenerative diseases. A pivotal moment arrived in 2019 when the company rebranded to Alterity Therapeutics to reflect its broadened focus. Key milestones include the strategic advancement of its leading drug compounds, ATH434, into clinical trials.
Competitive Advantages
Alterity Therapeutics holds a competitive edge through its proprietary drug development platform that targets misfolded proteins, a significant factor in neurodegenerative diseases. Its strategic focus on developing first-in-class treatments positions it uniquely within a market that has few effective therapeutic options.
Risk Factors
•Regulatory challenges in drug approval processes
•High R&D costs with uncertain return on investment
•Competitive pressure from larger pharmaceutical companies
Recent Developments
Last 6 months
Recently, Alterity has advanced its lead candidate ATH434 into Phase 2 clinical trials, with promising early data suggesting potential efficacy in treating Multiple System Atrophy, a form of Parkinsonian disorder.
Key People
Leadership team at Alterity Therapeutics
DS
David Stamler
CEO
Dr. David Stamler has extensive experience in the pharmaceutical industry, having held leadership positions in research and development. He joined Alterity as Chief Executive Officer bringing a wealth of clinical and regulatory expertise.
RS
Rene Sindlev
CFO
Rene Sindlev is the Chief Financial Officer at Alterity Therapeutics, with a background in accounting and financial management in the biotechnology sector.
Financial Reports
13 reports available
Quarterly Activities/Appendix 4C Cash Flow Report
Quarterly ReportOct 31, 2025via asx_announcements
Appendix 4E and 2025 Annual Report
Annual ResultsAug 29, 2025via asx_announcements
Quarterly Activities/Appendix 4C Cash Flow Report
Quarterly ReportJul 30, 2025via asx_announcements
Quarterly Activities/Appendix 4C Cash Flow Report
Quarterly ReportApr 30, 2025via asx_announcements
Half Yearly Report and Accounts
Half Year ResultsFeb 28, 2025via asx_announcements